Biomedicines

Biomedicines investigates the mechanisms of disease and novel therapies and pathways to promote health.

Focus of our research

Research within this theme focuses on understanding fundamental molecular mechanisms to provide novel insights into cellular processes and their regulation. Researchers use novel scientific and clinical approaches to support the development of modern therapeutic discovery, drug development, and disease prevention.

We have expertise in areas including target selection and validation, machine learning, computational drug design and disease modelling, comparative genomics, transcriptomics, epigenomics, lead molecule identification and optimisation.

Our interests include metabolic disease, cardiovascular disease, resilience to age-related decline, cardioprotective strategies, drug safety, SARS-CoV-2, cancer and the immune response.

Key researchers

• Dr Christopher Reynolds
• Dr Hoor Ayub
• Dr Bernard Burke
• Dr Isadora Clivatti-Furigo
• Dr Giuseppe Deganutti
• Dr Mike Dodd
• Dr Jennifer Greaves
• Dr Mark Harrison
• Dr Helen Maddock
• Dr Igor Morozov
• Dr Hardip Sandhu
• Dr Jason Tallis
• Dr Mark Turner
• Professor Mark Wheatley