Using novel computational modelling approaches to address biased agonism at the Adenosine A1 receptor

We seek to apply cutting-edge advanced sampling molecular dynamics simulations to address the complex biological issue of how G protein-coupled receptors (GPCRs) transition between multiple active states.


6-0! Promoting health through recreational football

This project focused on enhancing physical activity with aging people through recreational football activities.


Investigating GPCR:RAMP interactions using nanobodies

Professor Mark Wheatley and collaborators have been awarded a grant from the BBSRC to investigate the G-protein-coupled receptor (GPCR) family of proteins.


Transition state analysis to guide drug discovery

Professor Mark Wheatley and collaborators from Aston University, Dr John Simms and Professor David Poyner, have been awarded a grant of £177,497 from the BBSRC Follow-on Fund to develop new technology that will potentially revolutionise the drug discovery process.


Clinical Academic Research Development (CARD)

The main focus of CARD is to support allied health professionals working in the NHS undertake translational research, particularly in the field of nursing.


PostUraL tachycardia Syndrome Exercise (PulSE) study

A lifestyle intervention designed by people with POTS, for people with POTS.


Concentration or composition that is the question! How do exogenous fatty acids contribute to changes in metabolic flexibility of skeletal muscle?

Using Real-Time Cell Metabolic Analysis to establish how physiological and pathophysiological concentrations of FA impact mitochondrial function, capacity and substrate utilisation in human skeletal muscle cells.


Great expectations: a predictive processing account of human balance control

This research considers ways we can deliberately “manipulate” our predictive brains by using various interventions to modify our beliefs/expectations about an important perceptual-motor skills.


Cytokine and growth factor mediated regulation of cell polarity in liver regeneration and fibrosis

Dr Christopher Mee's project looking at the ability of the liver to fully regenerate after injury.


InoCardia: Novel human-cell based assay for assessment of cardiovascular liability

The aim of this project was to test the concept of a higher throughput functional cardiac cell contractile assay under truly physiological conditions, advancing information on how the heart behaves functionally and enabling the testing of inotropic drugs in these conditions.


The Blended Diet Study: the perceived benefits and risk of using a blended diet with children and young people with complex health needs and enteral feeding requirements

The use of a blended diet as an alternative to prescribed formula feeds has provoked strong opinion in research and among professionals. The aims of the report will be to examine the evidence for best practice with regards to providing a blended diet via gastrostomy tube.


Teenage Cancer Trust North-West Pilot Site Evaluation: A participatory action research project in the NW of England evaluating Teenage and Young Adult cancer services

Coventry University were tasked with providing a  longitudinal evaluation of the Teenage Cancer Trust's pilot scheme in the North West. 


Through the eyes of children, young people and families - Evaluation of the model of care delivered by WellChild Nurses

This project carried out a longitudinal evaluation of the model of care delivered to children, young people and families with complex care needs by organisation WellChild.


Evaluation of the Shuttletime Programme

This project examined the effect of engaging in the BWF Shuttle Time programme, compared to traditional Physical Education, on children's current and future engagement in sport and physical activity and health.


Using movement and story telling to enhance motor and cognitive development in preschoolers

This study sought to pilot an innovative intervention for pre-schoolers whereby movement is linked to storytelling in a fun and accessible manner.


InoCardia: Delivering Improved Cardiac Safety Liabilities for Therapeutic Drugs Using the Contractome-AI

The commercialisation of Professor Maddock's academic research started with a vision that there was a fundamental need within the Pharmaceutical Industry for the development of improved physiological relevant model to assess cardiac contractility.


Pilot of a teacher training intervention to deliver student-centred motor learning pedagogical approaches

This project is a pilot of a teacher training intervention to deliver student-centred motor learning pedagogical approaches and improve primary school children’s motor competence and motivation in physical education


Comparison of RR intervals and heart rate variability between disposable and reusable electrocardiography leads

The aim of the project is to assess heart rate variability using novel disposable ECG leads in healthy subjects, and to assess the agreement between heart rate variability measures obtained using disposable and reusable electrocardiography leads.


Addressing GPCR conformational flexibility

The large G protein coupled receptor (GPCR) family is a highly interesting target for drug design because a large proportion of current drugs bind to its members, and because the family offers much potential to exploit new targets.


Investigating the function and substrate interaction network of ABHD16A, a novel regulator of protein S-acylation

This study aims to characterise the molecular mechanisms and functions of a novel APT, ABHD16A.