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We seek to apply cutting-edge advanced sampling molecular dynamics simulations to address the complex biological issue of how G protein-coupled receptors (GPCRs) transition between multiple active states.
This project focused on enhancing physical activity with aging people through recreational football activities.
Professor Mark Wheatley and collaborators have been awarded a grant from the BBSRC to investigate the G-protein-coupled receptor (GPCR) family of proteins.
Professor Mark Wheatley and collaborators from Aston University, Dr John Simms and Professor David Poyner, have been awarded a grant of £177,497 from the BBSRC Follow-on Fund to develop new technology that will potentially revolutionise the drug discovery process.
The main focus of CARD is to support allied health professionals working in the NHS undertake translational research, particularly in the field of nursing.
A lifestyle intervention designed by people with POTS, for people with POTS.
Using Real-Time Cell Metabolic Analysis to establish how physiological and pathophysiological concentrations of FA impact mitochondrial function, capacity and substrate utilisation in human skeletal muscle cells.
This research considers ways we can deliberately “manipulate” our predictive brains by using various interventions to modify our beliefs/expectations about an important perceptual-motor skills.
Dr Christopher Mee's project looking at the ability of the liver to fully regenerate after injury.
The aim of this project was to test the concept of a higher throughput functional cardiac cell contractile assay under truly physiological conditions, advancing information on how the heart behaves functionally and enabling the testing of inotropic drugs in these conditions.
The use of a blended diet as an alternative to prescribed formula feeds has provoked strong opinion in research and among professionals. The aims of the report will be to examine the evidence for best practice with regards to providing a blended diet via gastrostomy tube.
Coventry University were tasked with providing a longitudinal evaluation of the Teenage Cancer Trust's pilot scheme in the North West.
This project carried out a longitudinal evaluation of the model of care delivered to children, young people and families with complex care needs by organisation WellChild.
This project examined the effect of engaging in the BWF Shuttle Time programme, compared to traditional Physical Education, on children's current and future engagement in sport and physical activity and health.
This study sought to pilot an innovative intervention for pre-schoolers whereby movement is linked to storytelling in a fun and accessible manner.
The commercialisation of Professor Maddock's academic research started with a vision that there was a fundamental need within the Pharmaceutical Industry for the development of improved physiological relevant model to assess cardiac contractility.
This project is a pilot of a teacher training intervention to deliver student-centred motor learning pedagogical approaches and improve primary school children’s motor competence and motivation in physical education
The aim of the project is to assess heart rate variability using novel disposable ECG leads in healthy subjects, and to assess the agreement between heart rate variability measures obtained using disposable and reusable electrocardiography leads.
The large G protein coupled receptor (GPCR) family is a highly interesting target for drug design because a large proportion of current drugs bind to its members, and because the family offers much potential to exploit new targets.
This study aims to characterise the molecular mechanisms and functions of a novel APT, ABHD16A.