Research Projects

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Addressing GPCR conformational flexibility

The large G protein coupled receptor (GPCR) family is a highly interesting target for drug design because a large proportion of current drugs bind to its members, and because the family offers much

Clinical Academic Research Development (CARD)

The main focus of CARD is to support allied health professionals working in the NHS undertake translational research, particularly in the field of nursing.

PostUraL tachycardia Syndrome Exercise (PulSE) study

A lifestyle intervention designed by people with POTS, for people with POTS.

InoCardia: Novel human-cell based assay for assessment of cardiovascular liability

InoCardia: Novel human-cell based assay for assessment of cardiovascular liability.

Fundamental Movement Skills, Physical Activity and Obesity in British Children

Dr Michael Duncan's project to understand how early development of fundamental movement skills might impact on physical activity and body fatness in British children.

Investigating GPCR:RAMP interactions using nanobodies

Professor Mark Wheatley and collaborators have been awarded a grant from the BBSRC to investigate the G-protein-coupled receptor (GPCR) family of proteins.

Bioleaching technology for the recovery of metals from Electronic Waste

Applications to Bioleaching technology to extract precious metals from Waste Electrical and Electronic Equipment (WEEE), whilst preserving the environment and preventing health-related issues

Comparison of RR intervals and heart rate variability between disposable and reusable electrocardiography leads

The aim of the project is to assess heart rate variability using novel disposable ECG leads in healthy subjects, and to assess the agreement between heart rate variability measures obtained using

Investigating the function and substrate interaction network of ABHD16A, a novel regulator of protein S-acylation

This study aims to characterise the molecular mechanisms and functions of a novel APT, ABHD16A.

6-0! Promoting health through recreational football

“6-0! – Promoting health through recreational football” focuses on enhancing physical activity with aging people through recreational football activities.

Transition state analysis to guide drug discovery

Professor Mark Wheatley and collaborators from Aston University, Dr John Simms and Professor David Poyner, have been awarded a grant of £177,497 from the BBSRC Follow-on Fund to develop new

Cytokine and growth factor mediated regulation of cell polarity in liver regeneration and fibrosis

Dr Christopher Mee's project looking at the ability of the liver to fully regenerate after injury.

Identification of novel double-stranded RNA elements in developing antibiotic resistance in the agricultural environment

The goal of the project is to identify and subsequently characterise the dsRNA dimension of the animal gut microflora (both the differential presence of antisense bound to mRNA and phage dsRNAs