Research
Projects
Research expertise within BIOCORE spans a number
of health-related areas. The following is a selection
of topics which are currently being investigated
with a number of national and international partners.
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•
Cancer bioinformatics and intelligent data
mining
• Epidemiological and aetiological
studies
• Image cytometry, histopathological
image analysis and visualisation
• Microsensor applications in biomedical
systems
• Agent-based telemedicine
• Multimedia information systems for
medical decision support
• Design of dental epidemiological
databases
• Clinical Knowledge Management
• Biomedical
ceramic implants
• Biomedical scaffolds for tissue
engineering
• Micromanufacturing
• Medical product and device design
• Computer aided engineering (CAE)
techniques in healthcare
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The following is a representative
sample of collaborative projects undertaken by
the group:
Non-invasive diagnosis of lymph
node metastasis in breast cancer patients (in
collaboration with the Cancer Research Unit, the
Departments of Surgery and Pathology, Newcastle
University, UK, and the Departments of Pathology
and Anatomy, University of Milan, Italy)
Investigation into the correlation
of disease progression with the metastasis-associated
genes h-mts1 and nm23 in carcinoma of the breast
(in collaboration with the Cancer Research Unit,
Newcastle University, UK, and the Departments
of General Pathology and Anatomy, University of
Milan, Italy)
Analysis of varying effects of
histopathological and immunohistochemical parameters
on survival of breast cancer patients (in collaboration
with the Cancer Research Unit and the Departments
of Surgery and Pathology, Newcastle University,
UK)
Identification of prominent biological
and experimental markers (p53, bcl-2, WAF-1) to
predict outcome for patients with prostate cancer
(in collaboration with the Department of Urology,
University of Sheffield, UK)
Analysis of incidence of disease
recurrence and/or progression in different stages
of bladder cancer (in collaboration with the Nephrology
and Urology Centre, Mansoura, Egypt)
Identification and classification
of colorectal tumour cells (in collaboration with
the Regional Medical Physics and Pathology Departments,
Freeman Hospital, Newcastle upon Tyne, UK)
Modelling invitation intervals
for breast screening (in collaboration with the
Coventry & Warwickshire Breast Screening Unit,
Coventry, UK)
Assessment of prognostic outcome
in ovarian cancer (in collaboration with the Department
of Gynaecological Oncology, Queen Elizabeth Hospital,
Gateshead, UK)
Interactive multimedia system
for breast awareness (in collaboration with University
Hospitals Coventry and Warwickshire NHS Trust,
Coventry, and WMG, University of Warwick, UK)
Analysis of diabetic retinopathy
(in collaboration with the George Eliot Hospital,
Nuneaton, UK)
Predictive analysis of perinatal
and neonatal databases (in collaboration with
Carleton University and Children’s Hospital
of Eastern Ontario, Canada)
Analysis of Hereditary Non-Polyposis
Colon Cancer (HNPCC) based on genetic and familial
databases (in collaboration with the Memorial
University of Newfoundland, Canada)
A Knowledge Management approach to breast cancer
screening prediction (in collaboration with the
Coventry & Warwickshire Breast Screening Unit,
Coventry, UK)
